According to the CDC, about 400,000 people died from opioid overdoses from 1999 to 2017. The number includes deaths from prescription and illegal opioids.

source https://finance.yahoo.com/m/da93668a-4d0e-3191-a5b9-6f95871719b7/opioid-crisis%3A-is-cannabis.html?.tsrc=rss